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KMID : 0356419990170010011
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Journal of Korean Andrology
1999 Volume.17 No. 1 p.11 ~ p.16
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Incidence of Vascular Risk Factors in Patients with Erectile Dysfunction Aged Over 40 Years: Comparison with Normal Men of Corresponding Age
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Seo Kyung-Keun
Lee Sung-Woon
Kim Sae-Chul
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Abstract
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Purpose: The incidences of four main vascular risk factors (VRFs)-diabetes mellitus (DM), smoking, hyperlipidemia (HLP), and hypertension-and obesity were investigated in men aged over 40 years with or without erectile dysfunction.
Patients and Methods: There were 943 patients with erectile dysfunction (mean age 55.0 years; range 40-73 years) and 242 normal men (mean age 50.6; range 40-71 years). Blood levels of the various lipid fractions (triglycerides, total cholesterol, low-density lipoprotein, high-density lipoprotein), body weight, and height were measured in all
subjects. Abnormal VRFs were defined as follows: hypertension=>160 ㎜Hg (systolic pressure) or 95 ㎜Hg (diastoic pressure), hyperlipidemia=at least one abnormal fraction (triglycerides>160 ㎎/㎗, total cholesterol >250 ㎎/㎗, LDL>150 ㎎/㎗), and obesity = >120% of ideal body weight. The presence or absence of DM, hypertension, smoking, and erectile dysfunction was determined by a self-reported subject questionnaire and history.
Results: The incidence of abnormal LDL was significantly (p<0.05) higher in patients than in the control men. The incidences of HLP, DM, and hypertension were significantly (all p<0.05) higher in the patients 40 to 59 years of age than in the control men of corresponding ages, but differences in the incidences of smoking and obesity were not statistically significant. Abnormal VRFs were significantly (all p<0.01) more common in patients aged 40 to 59 years than in the control men of the same ages. In men over 60 years of age, there were no differences between the patients and control
subjects in numbers of VRFs or the incidences of HLP, DM, and hypertension.
Conclusions: Especially in men 40 to 59 years of age, DM, HLP, and hypertension were significantly correlated with erectile dysfunction. The aging process, rather than such specific risk factors, might be a main cause of erectile dysfunction in men aged over 60 years.
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KEYWORD
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Erectile dysfunction, Vascular risk factors,
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